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Hormone replacement therapy for women

Hormone Replacement Therapy: Reclaim Your Energy, Vitality, and Performance

Hormonal decline isn’t something you have to accept. Whether you’re navigating perimenopause, menopause, PCOS, or simply dealing with hormones that are “normal” but far from optimal, ApexBlood connects you with physician-supervised hormone replacement therapy designed for women who refuse to settle for suboptimal.

100% online. Real doctors. Fast results. Competitively priced.

Apex HRT Protocol kit with estradiol, progesterone tablets and testosterone cream
HRT group of woman

Why Hormones Matter for Performance and Quality of Life

Estrogen, progesterone, and testosterone aren’t just reproductive hormones. They’re performance hormones that affect energy, mental clarity, body composition, mood, sleep, and vitality.

When your hormones are suboptimal, everything suffers. Hormonal imbalance shows up as more than just hot flashes and irregular periods. It manifests as crushing fatigue and low motivation, brain fog and poor focus, weight gain (especially around the midsection) and difficulty losing fat, mood swings, anxiety, and depression, sleep disruptions and night sweats, low libido and reduced sexual satisfaction, joint pain and muscle loss, and skin changes including dryness and thinning.

Your doctor might tell you these symptoms are “just part of being a woman” or “normal for your age.” We’ll tell you that optimal hormones can restore your energy, sharpen your mind, improve your body composition, and give you back the vitality you thought was gone forever.

The process

How ApexBlood HRT Works

Care Team on Phone
Step 1

Free Consultation with Our Care Team

Start with a free consultation to discuss your symptoms, goals, and whether HRT is right for you. No obligation. If you don’t qualify, you don’t pay.

Dr J having a telemedicine visit
Step 2

Physician Evaluation

If you’re a good candidate, you’ll authorize the program and speak with one of our licensed physicians. They’ll review your health history and determine the right approach for your individual needs.

Blood Draw
Step 3

Blood Testing (If Needed)

Already have recent labs showing your hormone levels? You may be able to skip this step. If not, we’ll order comprehensive testing to establish your baseline and identify which hormones need optimization. Testing is included in your first month.

Treatment delivered in an unmarked box
Step 4

Treatment Delivery

Once approved, your physician prescribes a customized protocol. Medication and shipping are all included. Everything arrives at your door. We will be with you every step of the way.

Options

Treatment Options: Customized to You

We’re not a cookie-cutter HRT clinic. Your physician determines the best approach based on your age, symptoms, health history, and goals.

Estrogen Therapy

Estrogen Therapy

Estrogen is the primary hormone that declines during perimenopause and menopause. Replacing it can dramatically improve hot flashes, night sweats, vaginal dryness, mood, bone density, and cognitive function. We offer multiple forms including oral, transdermal (patches or creams), and bioidentical options. Your physician will determine which form and dosage is right for you.

Apex HRT Protocol kit with estradiol, progesterone tablets and testosterone cream
Hormones · Rx

Bioidentical Hormone Replacement Therapy (BHRT)

Bioidentical hormones are plant-derived and chemically identical to the hormones your body produces naturally. Many women prefer BHRT for this reason. Your physician will discuss whether bioidentical or synthetic hormones are the best fit for your situation.

Learn more →
Progesterone Therapy

Progesterone Therapy

Progesterone balances estrogen, protects the uterine lining, and improves sleep quality and mood stability. For women with a uterus taking estrogen, progesterone is essential to prevent endometrial hyperplasia. We offer both bioidentical and synthetic forms depending on your needs and preferences.

Testosterone for Women

Testosterone for Women

Testosterone isn’t just a male hormone. Women produce it naturally, and it plays a critical role in energy, libido, muscle mass, motivation, and mental clarity. Many women experience dramatic improvements in vitality and sexual satisfaction when testosterone is optimized. We offer compounded testosterone creams tailored to women’s needs.

PCOS Treatment

PCOS Treatment

Polycystic Ovary Syndrome (PCOS) affects 1 in 10 women and is characterized by high androgens, irregular periods, insulin resistance, and difficulty losing weight. Our physicians use a combination of hormonal treatments, metabolic medications like metformin, and lifestyle guidance to help you manage PCOS symptoms and restore hormonal balance.

Rx only. A licensed clinician reviews your health history and labs and prescribes only when treatment is appropriate.

Included

What’s Included

Everything you need to optimize your hormones, delivered to your door

  • Physician-prescribed hormones (customized to your protocol)
  • Ongoing monitoring and physician access
  • Regular care team check-ins
  • Free shipping.

No hidden fees. No upselling unnecessary add-ons. Just physician-supervised optimization.

Pricing

First MonthIncludes initial physician consultation, hormone blood testing (if needed), and your first month of treatment. If you don’t qualify for treatment after testing, you’ll receive a refund minus blood work.
Ongoing MonthsCompetitively priced monthly subscription includes medication, shipping, and ongoing monitoring.

Frequently Asked Questions

Do I need blood work to get started?

If you have recent labs (within the past few months) showing your hormone levels, you may not need new testing. If you don’t have labs or they’re outdated, we’ll order comprehensive hormone testing. Testing is included in your first month if needed. Get a free medical consultation here.

How quickly can I get started?

Fast. Schedule a free consultation with our care team. If you’re a good candidate, you’ll speak with a physician, get approved, complete any necessary testing, and have medication shipped to your door. Most patients are started within days to a couple weeks depending on whether labs are needed.

What states do you serve?

All 50 states. We’re a fully online platform, so location doesn’t limit access to physician-supervised HRT.

How often will I need follow-up labs?

This varies based on your treatment protocol and how you’re responding. Typically, follow-up labs are done a few months after starting to ensure your levels are optimized, and then annually or as needed. Your physician will determine the right monitoring schedule for you.

What if my levels come back normal or high?

Our physicians prescribe based on medical necessity and symptoms. If your hormone levels are already in a healthy range and you’re not experiencing symptoms, HRT may not be appropriate. If you’ve already authorized the program and labs show you don’t qualify, you’ll receive a refund minus blood work. We don’t prescribe when it’s not warranted.

Can I adjust my dosing or injection frequency?

Yes. HRT is highly individualized. Some women need more estrogen, others need less. Some do better with progesterone at night for sleep, others prefer morning dosing. Your physician will work with you to find what optimizes your symptoms with minimal side effects.

Is HRT safe? What about the risks?

Modern HRT, when properly prescribed and monitored, is safe for most women. The outdated fear of HRT stems from a flawed 2002 study that has since been reanalyzed and largely debunked. Current evidence shows that HRT started during perimenopause or early menopause (before age 60 or within 10 years of menopause) has significant benefits for quality of life, bone density, cardiovascular health, and cognitive function. Your physician will review your individual risk factors and determine if HRT is safe for you.

What’s the difference between bioidentical and synthetic hormones?

Bioidentical hormones are chemically identical to the hormones your body produces naturally. They’re derived from plant sources and are often preferred by women who want hormones that match their natural biology. Synthetic hormones are slightly different in structure but are still effective. Your physician will discuss the pros and cons of each option based on your preferences and medical history.

Can HRT help with weight loss?

HRT can make weight loss easier by restoring your metabolic function, improving energy for exercise, and reducing hormonal drivers of fat storage (especially around the midsection). However, HRT alone won’t cause weight loss. It works best when combined with proper nutrition and exercise. For women with PCOS or insulin resistance, adding metformin to HRT can significantly improve metabolic health and weight management.

Will HRT help with PCOS?

Yes. PCOS is a hormonal imbalance characterized by high androgens, insulin resistance, and irregular periods. Treatment often includes hormonal contraceptives to regulate cycles, anti-androgens to reduce symptoms like acne and hirsutism, and metformin to improve insulin sensitivity. Your physician will create a personalized PCOS treatment plan based on your specific symptoms and goals.

Can I still get HRT if I have a history of breast cancer or blood clots?

This depends on your individual medical history. Certain conditions like active breast cancer or a history of blood clots may make traditional HRT inappropriate. However, some women in these situations can still use localized treatments (like vaginal estrogen) or alternative therapies. Your physician will carefully review your history and determine what’s safe for you.

Often paired with

Build your hormones protocol.

Rx only. A licensed clinician reviews your health history and labs and prescribes only when treatment is appropriate.

Labs that guide this treatment

Test first. Track as you go.

Your clinician uses these panels to dose HRT Protocol safely and prove it’s working. Or start with the full Apex Complete panel.

Hormones

Women's Hormone Assessment

$57

FSH, LH, estradiol, testosterone, SHBG, TSH. 10 biomarkers.

See all 10 biomarkers
Hormones

Menopause Health

$137

Hormones, lipids, metabolic, thyroid and ESR. 55 biomarkers.

See all 55 biomarkers

Ready to Stop Settling for Suboptimal?

Your hormones shouldn’t dictate your quality of life. Whether you’re dealing with perimenopause, menopause, PCOS, or simply hormones that are “normal” but far from peak, physician-supervised HRT can help you reclaim your energy, mental clarity, and vitality.

Start with a free consultation. If you don’t qualify, you don’t pay. If you do, you’ll have everything you need to optimize your hormones delivered to your door.

Stop accepting “normal for your age” when optimal is possible.

Apex Complete · 76 biomarkers$207Get started